diff --git a/configure.ac b/configure.ac
index e8a3f68a64..b01cf5af8d 100644
--- a/configure.ac
+++ b/configure.ac
@@ -1241,7 +1241,7 @@ dnl Do not change "-I/usr/include" to "-isystem /usr/include" because that
 dnl is not necessary (/usr/include is already a system directory) and because
 dnl it would break GCC's #include_next.
 AC_DEFUN([SUPPRESS_WARNINGS],
-         [$(echo $1 |${SED} -E -e 's/(^| )-I/\1-isystem /g' -e 's;-isystem /usr/include([/ ]|$);-I/usr/include\1;g')])
+         [[$(echo $1 |${SED} -E -e 's/(^| )-I/\1-isystem /g' -e 's;-isystem /usr/include/*( |$);-I/usr/include\1;g')]])
 
 dnl enable-fuzz should disable all other targets
 if test "x$enable_fuzz" = "xyes"; then