diff --git a/ci/matrix.sh b/ci/matrix.sh
index cbdf3a186e..7ff8186d3b 100755
--- a/ci/matrix.sh
+++ b/ci/matrix.sh
@@ -40,7 +40,7 @@ if [ "$BUILD_TARGET" = "arm-linux" ]; then
   export CHECK_DOC=1
   # -Wno-psabi is to disable ABI warnings: "note: parameter passing for argument of type ... changed in GCC 7.1"
   # This could be removed once the ABI change warning does not show up by default
-  export BITCOIN_CONFIG="--enable-glibc-back-compat --enable-reduce-exports --enable-werror CXXFLAGS=-Wno-psabi"
+  export BITCOIN_CONFIG="--enable-glibc-back-compat --enable-reduce-exports --enable-suppress-external-warnings --enable-werror CXXFLAGS=-Wno-psabi"
   export RUN_UNITTESTS=false
   export RUN_INTEGRATIONTESTS=false
 elif [ "$BUILD_TARGET" = "win64" ]; then
@@ -62,7 +62,7 @@ elif [ "$BUILD_TARGET" = "linux64" ]; then
 elif [ "$BUILD_TARGET" = "linux64_cxx17" ]; then
   export HOST=x86_64-unknown-linux-gnu
   export DEP_OPTS="NO_UPNP=1 DEBUG=1"
-  export BITCOIN_CONFIG="--enable-zmq --enable-glibc-back-compat --enable-reduce-exports --enable-crash-hooks --enable-c++17 --enable-werror --with-sanitizers=undefined"
+  export BITCOIN_CONFIG="--enable-zmq --enable-glibc-back-compat --enable-reduce-exports --enable-crash-hooks --enable-c++17 --enable-suppress-external-warnings --enable-werror --with-sanitizers=undefined"
   export CPPFLAGS="-DDEBUG_LOCKORDER -DENABLE_DASH_DEBUG -DARENA_DEBUG"
   export PYZMQ=true
   export RUN_INTEGRATIONTESTS=false
diff --git a/configure.ac b/configure.ac
index 2ef0798a39..9b01f90c35 100644
--- a/configure.ac
+++ b/configure.ac
@@ -172,6 +172,16 @@ AC_ARG_ENABLE([ccache],
   [use_ccache=$enableval],
   [use_ccache=auto])
 
+dnl Suppress warnings from external headers (e.g. Boost, Qt).
+dnl May be useful if warnings from external headers clutter the build output
+dnl too much, so that it becomes difficult to spot Bitcoin Core warnings
+dnl or if they cause a build failure with --enable-werror.
+AC_ARG_ENABLE([suppress-external-warnings],
+  [AS_HELP_STRING([--enable-suppress-external-warnings],
+                  [Suppress warnings from external headers (default is no)])],
+  [suppress_external_warnings=$enableval],
+  [suppress_external_warnings=no])
+
 AC_ARG_ENABLE([lcov],
   [AS_HELP_STRING([--enable-lcov],
   [enable lcov testing (default is no)])],
@@ -1089,9 +1099,24 @@ AC_SUBST(LEVELDB_CPPFLAGS)
 AC_SUBST(LIBLEVELDB)
 AC_SUBST(LIBMEMENV)
 
+dnl SUPPRESSED_CPPFLAGS=SUPPRESS_WARNINGS([$SOME_CPPFLAGS])
+dnl Replace -I with -isystem in $SOME_CPPFLAGS to suppress warnings from
+dnl headers from its include directories and return the result.
+dnl See -isystem documentation:
+dnl https://gcc.gnu.org/onlinedocs/gcc/Directory-Options.html
+dnl https://clang.llvm.org/docs/ClangCommandLineReference.html#cmdoption-clang-isystem-directory
+dnl Do not change "-I/usr/include" to "-isystem /usr/include" because that
+dnl is not necessary (/usr/include is already a system directory) and because
+dnl it would break GCC's #include_next.
+AC_DEFUN([SUPPRESS_WARNINGS],
+         [$(echo $1 |${SED} -E -e 's/(^| )-I/\1-isystem /g' -e 's;-isystem /usr/include([/ ]|$);-I/usr/include\1;g')])
+
 if test x$enable_wallet != xno; then
     dnl Check for libdb_cxx only if wallet enabled
     BITCOIN_FIND_BDB48
+    if test x$suppress_external_warnings != xno ; then
+        BDB_CPPFLAGS=SUPPRESS_WARNINGS($BDB_CPPFLAGS)
+    fi
 fi
 
 dnl Check for libminiupnpc (optional)
@@ -1128,6 +1153,14 @@ BITCOIN_QT_INIT
 dnl sets $bitcoin_enable_qt, $bitcoin_enable_qt_test, $bitcoin_enable_qt_dbus
 BITCOIN_QT_CONFIGURE([5.5.1])
 
+dnl Keep a copy of the original $QT_INCLUDES and use it when invoking qt's moc
+QT_INCLUDES_UNSUPPRESSED=$QT_INCLUDES
+if test x$suppress_external_warnings != xno ; then
+  QT_INCLUDES=SUPPRESS_WARNINGS($QT_INCLUDES)
+  QT_DBUS_INCLUDES=SUPPRESS_WARNINGS($QT_DBUS_INCLUDES)
+  QT_TEST_INCLUDES=SUPPRESS_WARNINGS($QT_TEST_INCLUDES)
+fi
+
 if test x$build_bitcoin_cli$build_bitcoin_tx$build_bitcoind$bitcoin_enable_qt$use_tests$use_bench = xnononononono; then
     use_boost=no
 else
@@ -1149,6 +1182,10 @@ AX_BOOST_FILESYSTEM
 AX_BOOST_THREAD
 AX_BOOST_CHRONO
 
+if test x$suppress_external_warnings != xno; then
+    BOOST_CPPFLAGS=SUPPRESS_WARNINGS($BOOST_CPPFLAGS)
+fi
+
 dnl Boost 1.56 through 1.62 allow using std::atomic instead of its own atomic
 dnl counter implementations. In 1.63 and later the std::atomic approach is default.
 m4_pattern_allow(DBOOST_AC_USE_STD_ATOMIC) dnl otherwise it's treated like a macro
diff --git a/src/Makefile.qt.include b/src/Makefile.qt.include
index 260df471c1..6464055d14 100644
--- a/src/Makefile.qt.include
+++ b/src/Makefile.qt.include
@@ -477,11 +477,11 @@ ui_%.h: %.ui
 	$(AM_V_GEN) QT_SELECT=$(QT_SELECT) $(UIC) -o $@ $< || (echo "Error creating $@"; false)
 
 %.moc: %.cpp
-	$(AM_V_GEN) QT_SELECT=$(QT_SELECT) $(MOC) $(DEFAULT_INCLUDES) $(QT_INCLUDES) $(MOC_DEFS) $< | \
+	$(AM_V_GEN) QT_SELECT=$(QT_SELECT) $(MOC) $(DEFAULT_INCLUDES) $(QT_INCLUDES_UNSUPPRESSED) $(MOC_DEFS) $< | \
 	  $(SED) -e '/^\*\*.*Created:/d' -e '/^\*\*.*by:/d' > $@
 
 moc_%.cpp: %.h
-	$(AM_V_GEN) QT_SELECT=$(QT_SELECT) $(MOC) $(DEFAULT_INCLUDES) $(QT_INCLUDES) $(MOC_DEFS) $< | \
+	$(AM_V_GEN) QT_SELECT=$(QT_SELECT) $(MOC) $(DEFAULT_INCLUDES) $(QT_INCLUDES_UNSUPPRESSED) $(MOC_DEFS) $< | \
 	  $(SED) -e '/^\*\*.*Created:/d' -e '/^\*\*.*by:/d' > $@
 
 %.qm: %.ts