diff --git a/share/qt/Info.plist.in b/share/qt/Info.plist.in
index 41f37eb43c..ff1f26cdd9 100644
--- a/share/qt/Info.plist.in
+++ b/share/qt/Info.plist.in
@@ -97,9 +97,6 @@
   <key>NSHighResolutionCapable</key>
     <string>True</string>
 
-  <key>LSAppNapIsDisabled</key>
-    <string>True</string>
-
   <key>NSRequiresAquaSystemAppearance</key>
     <string>True</string>
 
diff --git a/src/Makefile.qt.include b/src/Makefile.qt.include
index 56a6dca189..26eb4dfc85 100644
--- a/src/Makefile.qt.include
+++ b/src/Makefile.qt.include
@@ -103,7 +103,8 @@ QT_MOC_CPP = \
 
 BITCOIN_MM = \
   qt/macdockiconhandler.mm \
-  qt/macnotificationhandler.mm
+  qt/macnotificationhandler.mm \
+  qt/macos_appnap.mm
 
 QT_MOC = \
   qt/dash.moc \
@@ -142,6 +143,7 @@ BITCOIN_QT_H = \
   qt/intro.h \
   qt/macdockiconhandler.h \
   qt/macnotificationhandler.h \
+  qt/macos_appnap.h \
   qt/modaloverlay.h \
   qt/masternodelist.h \
   qt/networkstyle.h \
diff --git a/src/qt/bitcoingui.cpp b/src/qt/bitcoingui.cpp
index cc90e89d64..b6c4ca816a 100644
--- a/src/qt/bitcoingui.cpp
+++ b/src/qt/bitcoingui.cpp
@@ -24,6 +24,7 @@
 #include "utilitydialog.h"
 
 #ifdef ENABLE_WALLET
+#include "privatesend/privatesend-client.h"
 #include "walletframe.h"
 #include "walletmodel.h"
 #endif // ENABLE_WALLET
@@ -266,6 +267,10 @@ BitcoinGUI::BitcoinGUI(const PlatformStyle *_platformStyle, const NetworkStyle *
         connect(progressBar, SIGNAL(clicked(QPoint)), this, SLOT(showModalOverlay()));
     }
 #endif
+
+#ifdef Q_OS_MAC
+    m_app_nap_inhibitor = new CAppNapInhibitor;
+#endif
 }
 
 BitcoinGUI::~BitcoinGUI()
@@ -277,6 +282,7 @@ BitcoinGUI::~BitcoinGUI()
     if(trayIcon) // Hide tray icon, as deleting will let it linger until quit (on Ubuntu)
         trayIcon->hide();
 #ifdef Q_OS_MAC
+    delete m_app_nap_inhibitor;
     delete appMenuBar;
     MacDockIconHandler::cleanup();
 #endif
@@ -950,6 +956,19 @@ void BitcoinGUI::updateHeadersSyncProgressLabel()
 
 void BitcoinGUI::setNumBlocks(int count, const QDateTime& blockDate, double nVerificationProgress, bool header)
 {
+#ifdef Q_OS_MAC
+    // Disabling macOS App Nap on initial sync, disk, reindex operations and mixing.
+    bool disableAppNap = !masternodeSync.IsSynced();
+#ifdef ENABLE_WALLET
+    disableAppNap |= privateSendClient.fPrivateSendRunning;
+#endif // ENABLE_WALLET
+    if (disableAppNap) {
+        m_app_nap_inhibitor->disableAppNap();
+    } else {
+        m_app_nap_inhibitor->enableAppNap();
+    }
+#endif // Q_OS_MAC
+
     if (modalOverlay)
     {
         if (header)
diff --git a/src/qt/bitcoingui.h b/src/qt/bitcoingui.h
index df1fd19933..ef08389982 100644
--- a/src/qt/bitcoingui.h
+++ b/src/qt/bitcoingui.h
@@ -19,6 +19,10 @@
 #include <QPushButton>
 #include <QSystemTrayIcon>
 
+#ifdef Q_OS_MAC
+#include <qt/macos_appnap.h>
+#endif
+
 class ClientModel;
 class NetworkStyle;
 class Notificator;
@@ -131,6 +135,10 @@ private:
     HelpMessageDialog *helpMessageDialog;
     ModalOverlay *modalOverlay;
 
+#ifdef Q_OS_MAC
+    CAppNapInhibitor* m_app_nap_inhibitor = nullptr;
+#endif
+
     /** Keep track of previous number of blocks, to detect progress */
     int prevBlocks;
     int spinnerFrame;
diff --git a/src/qt/macos_appnap.h b/src/qt/macos_appnap.h
new file mode 100644
index 0000000000..8c2cd840b0
--- /dev/null
+++ b/src/qt/macos_appnap.h
@@ -0,0 +1,24 @@
+// Copyright (c) 2011-2018 The Bitcoin Core developers
+// Distributed under the MIT software license, see the accompanying
+// file COPYING or http://www.opensource.org/licenses/mit-license.php.
+
+#ifndef BITCOIN_QT_MACOS_APPNAP_H
+#define BITCOIN_QT_MACOS_APPNAP_H
+
+#include <memory>
+
+class CAppNapInhibitor final
+{
+public:
+    explicit CAppNapInhibitor();
+    ~CAppNapInhibitor();
+
+    void disableAppNap();
+    void enableAppNap();
+
+private:
+    class CAppNapImpl;
+    std::unique_ptr<CAppNapImpl> impl;
+};
+
+#endif // BITCOIN_QT_MACOS_APPNAP_H
diff --git a/src/qt/macos_appnap.mm b/src/qt/macos_appnap.mm
new file mode 100644
index 0000000000..363c60091f
--- /dev/null
+++ b/src/qt/macos_appnap.mm
@@ -0,0 +1,71 @@
+// Copyright (c) 2011-2018 The Bitcoin Core developers
+// Distributed under the MIT software license, see the accompanying
+// file COPYING or http://www.opensource.org/licenses/mit-license.php.
+
+#include "macos_appnap.h"
+
+#include <AvailabilityMacros.h>
+#include <Foundation/NSProcessInfo.h>
+#include <Foundation/Foundation.h>
+
+class CAppNapInhibitor::CAppNapImpl
+{
+public:
+    ~CAppNapImpl()
+    {
+        if(activityId)
+            enableAppNap();
+    }
+
+    void disableAppNap()
+    {
+        if (!activityId)
+        {
+            @autoreleasepool {
+                const NSActivityOptions activityOptions =
+                NSActivityUserInitiatedAllowingIdleSystemSleep &
+                ~(NSActivitySuddenTerminationDisabled |
+                NSActivityAutomaticTerminationDisabled);
+
+                id processInfo = [NSProcessInfo processInfo];
+                if ([processInfo respondsToSelector:@selector(beginActivityWithOptions:reason:)])
+                {
+                    activityId = [processInfo beginActivityWithOptions: activityOptions reason:@"Temporarily disable App Nap for dash-qt."];
+                    [activityId retain];
+                }
+            }
+        }
+    }
+
+    void enableAppNap()
+    {
+        if(activityId)
+        {
+            @autoreleasepool {
+                id processInfo = [NSProcessInfo processInfo];
+                if ([processInfo respondsToSelector:@selector(endActivity:)])
+                    [processInfo endActivity:activityId];
+
+                [activityId release];
+                activityId = nil;
+            }
+        }
+    }
+
+private:
+    NSObject* activityId;
+};
+
+CAppNapInhibitor::CAppNapInhibitor() : impl(new CAppNapImpl()) {}
+
+CAppNapInhibitor::~CAppNapInhibitor() = default;
+
+void CAppNapInhibitor::disableAppNap()
+{
+    impl->disableAppNap();
+}
+
+void CAppNapInhibitor::enableAppNap()
+{
+    impl->enableAppNap();
+}