diff --git a/.gitlab-ci.yml b/.gitlab-ci.yml
index 4ab688c672..755d40a4c9 100644
--- a/.gitlab-ci.yml
+++ b/.gitlab-ci.yml
@@ -251,6 +251,13 @@ linux64_cxx20-build:
   variables:
     BUILD_TARGET: linux64_cxx20
 
+linux64_sqlite-build:
+  extends: .build-template
+  needs:
+    - x86_64-pc-linux-gnu-debug
+  variables:
+    BUILD_TARGET: linux64_sqlite
+
 linux64_fuzz-build:
   extends: .build-template
   needs:
@@ -312,6 +319,13 @@ linux64-test:
   variables:
     BUILD_TARGET: linux64
 
+linux64_sqlite-test:
+  extends: .test-template
+  needs:
+    - linux64_sqlite-build
+  variables:
+    BUILD_TARGET: linux64_sqlite
+
 linux64_tsan-test:
   extends:
     - .test-template
diff --git a/ci/dash/matrix.sh b/ci/dash/matrix.sh
index 21028410a4..6b21a0f5d8 100755
--- a/ci/dash/matrix.sh
+++ b/ci/dash/matrix.sh
@@ -30,6 +30,8 @@ elif [ "$BUILD_TARGET" = "linux64_fuzz" ]; then
   source ./ci/test/00_setup_env_native_fuzz.sh
 elif [ "$BUILD_TARGET" = "linux64_cxx20" ]; then
   source ./ci/test/00_setup_env_native_cxx20.sh
+elif [ "$BUILD_TARGET" = "linux64_sqlite" ]; then
+  source ./ci/test/00_setup_env_native_sqlite.sh
 elif [ "$BUILD_TARGET" = "linux64_nowallet" ]; then
   source ./ci/test/00_setup_env_native_nowallet.sh
 elif [ "$BUILD_TARGET" = "mac" ]; then
diff --git a/ci/test/00_setup_env_native_sqlite.sh b/ci/test/00_setup_env_native_sqlite.sh
new file mode 100644
index 0000000000..e97fd0ebb9
--- /dev/null
+++ b/ci/test/00_setup_env_native_sqlite.sh
@@ -0,0 +1,12 @@
+#!/usr/bin/env bash
+#
+# Copyright (c) 2019 The Bitcoin Core developers
+# Distributed under the MIT software license, see the accompanying
+# file COPYING or http://www.opensource.org/licenses/mit-license.php.
+
+export LC_ALL=C.UTF-8
+
+export PACKAGES="python3-zmq qtbase5-dev qttools5-dev-tools libdbus-1-dev libharfbuzz-dev"
+export DEP_OPTS="NO_BDB=1 NO_UPNP=1 DEBUG=1"
+export GOAL="install"
+export BITCOIN_CONFIG="--enable-zmq --enable-glibc-back-compat --enable-reduce-exports --with-sqlite --without-bdb LDFLAGS=-static-libstdc++"