diff --git a/.gitignore b/.gitignore
index e5b3265f88..949403cc23 100644
--- a/.gitignore
+++ b/.gitignore
@@ -161,7 +161,6 @@ cmake-build-debug
 # clang-check
 *.plist
 
-osx_volname
 dist/
 
 /guix-build-*
diff --git a/Makefile.am b/Makefile.am
index 887f9ad4ec..5c628914ed 100644
--- a/Makefile.am
+++ b/Makefile.am
@@ -119,9 +119,6 @@ OSX_APP_BUILT=$(OSX_APP)/Contents/PkgInfo $(OSX_APP)/Contents/Resources/empty.lp
   $(OSX_APP)/Contents/Resources/dash.icns $(OSX_APP)/Contents/Info.plist \
   $(OSX_APP)/Contents/MacOS/Dash-Qt $(OSX_APP)/Contents/Resources/Base.lproj/InfoPlist.strings
 
-osx_volname:
-	echo $(OSX_VOLNAME) >$@
-
 if BUILD_DARWIN
 $(OSX_DMG): $(OSX_APP_BUILT) $(OSX_PACKAGING)
 	$(PYTHON) $(OSX_DEPLOY_SCRIPT) $(OSX_APP) $(OSX_VOLNAME) -translations-dir=$(QT_TRANSLATION_DIR) -dmg
@@ -323,7 +320,7 @@ clean-docs:
 clean-local: clean-docs
 	rm -rf coverage_percent.txt test_dash.coverage/ total.coverage/ fuzz.coverage/ test/tmp/ cache/ $(OSX_APP)
 	rm -rf test/functional/__pycache__ test/functional/test_framework/__pycache__ test/cache share/rpcauth/__pycache__
-	rm -rf osx_volname dist/
+	rm -rf dist/
 
 test-security-check:
 if TARGET_DARWIN
diff --git a/build-aux/m4/bitcoin_qt.m4 b/build-aux/m4/bitcoin_qt.m4
index 186a89721d..89f3e188ee 100644
--- a/build-aux/m4/bitcoin_qt.m4
+++ b/build-aux/m4/bitcoin_qt.m4
@@ -137,7 +137,6 @@ AC_DEFUN([BITCOIN_QT_CONFIGURE],[
       fi
     fi
 
-    AC_DEFINE(QT_STATICPLUGIN, 1, [Define this symbol if qt plugins are static])
     if test "x$TARGET_OS" != xandroid; then
       _BITCOIN_QT_CHECK_STATIC_PLUGIN([QMinimalIntegrationPlugin], [-lqminimal])
       AC_DEFINE(QT_QPA_PLATFORM_MINIMAL, 1, [Define this symbol if the minimal qt platform exists])
diff --git a/contrib/guix/libexec/build.sh b/contrib/guix/libexec/build.sh
index e5fc7cb275..2618bfe226 100755
--- a/contrib/guix/libexec/build.sh
+++ b/contrib/guix/libexec/build.sh
@@ -236,7 +236,6 @@ mkdir -p "$OUTDIR"
 # CONFIGFLAGS
 CONFIGFLAGS+=" --enable-reduce-exports --disable-bench --disable-gui-tests --disable-fuzz-binary"
 case "$HOST" in
-    *linux*) CONFIGFLAGS+=" --disable-threadlocal" ;;
     *mingw*) CONFIGFLAGS+=" --disable-miner" ;;
 esac
 
@@ -324,11 +323,9 @@ mkdir -p "$DISTSRC"
 
     case "$HOST" in
         *darwin*)
-            make osx_volname ${V:+V=1}
             make deploydir ${V:+V=1}
             mkdir -p "unsigned-app-${HOST}"
             cp  --target-directory="unsigned-app-${HOST}" \
-                osx_volname \
                 contrib/macdeploy/detached-sig-create.sh \
                 "${BASEPREFIX}/${HOST}"/native/bin/dmg
             mv --target-directory="unsigned-app-${HOST}" dist
diff --git a/depends/funcs.mk b/depends/funcs.mk
index 324475b79c..e76a69ffce 100644
--- a/depends/funcs.mk
+++ b/depends/funcs.mk
@@ -170,12 +170,19 @@ ifneq ($($(1)_ldflags),)
 $(1)_autoconf += LDFLAGS="$$($(1)_ldflags)"
 endif
 
+# We hardcode the library install path to "lib" to match the PKG_CONFIG_PATH
+# setting in depends/config.site.in, which also hardcodes "lib".
+# Without this setting, CMake by default would use the OS library
+# directory, which might be "lib64" or something else, not "lib", on multiarch systems.
 $(1)_cmake=env CC="$$($(1)_cc)" \
                CFLAGS="$$($(1)_cppflags) $$($(1)_cflags)" \
                CXX="$$($(1)_cxx)" \
                CXXFLAGS="$$($(1)_cppflags) $$($(1)_cxxflags)" \
                LDFLAGS="$$($(1)_ldflags)" \
-             cmake -DCMAKE_INSTALL_PREFIX:PATH="$$($($(1)_type)_prefix)" $$($(1)_config_opts)
+               cmake -DCMAKE_INSTALL_PREFIX:PATH="$$($($(1)_type)_prefix)" \
+               -DCMAKE_INSTALL_LIBDIR=lib/ \
+               -DCMAKE_POSITION_INDEPENDENT_CODE=ON \
+               $$($(1)_config_opts)
 ifeq ($($(1)_type),build)
 $(1)_cmake += -DCMAKE_INSTALL_RPATH:PATH="$$($($(1)_type)_prefix)/lib"
 else
diff --git a/depends/hosts/default.mk b/depends/hosts/default.mk
index 258619a9d0..57e71ad55f 100644
--- a/depends/hosts/default.mk
+++ b/depends/hosts/default.mk
@@ -29,8 +29,13 @@ host_$1=$$($(host_arch)_$(host_os)_$1)
 endef
 
 define add_host_flags_func
+ifeq ($(filter $(origin $1),undefined default),)
+$(host_arch)_$(host_os)_$1 =
+$(host_arch)_$(host_os)_$(release_type)_$1 = $($1)
+else
 $(host_arch)_$(host_os)_$1 += $($(host_os)_$1)
 $(host_arch)_$(host_os)_$(release_type)_$1 += $($(host_os)_$(release_type)_$1)
+endif
 host_$1 = $$($(host_arch)_$(host_os)_$1)
 host_$(release_type)_$1 = $$($(host_arch)_$(host_os)_$(release_type)_$1)
 endef
diff --git a/depends/packages.md b/depends/packages.md
index 6d09f8c97b..1300d6de03 100644
--- a/depends/packages.md
+++ b/depends/packages.md
@@ -164,7 +164,7 @@ From the [Gentoo Wiki entry](https://wiki.gentoo.org/wiki/Project:Quality_Assura
 >  ecosystem, as it leads to a massive number of unnecessary rebuilds.
 
 Where possible, packages are built with Position Independant Code. Either using
-the autotools `--with-pic` flag, or `DCMAKE_POSITION_INDEPENDENT_CODE` with CMake.
+the Autotools `--with-pic` flag, or `CMAKE_POSITION_INDEPENDENT_CODE` with CMake.
 
 ## Secondary dependencies:
 
diff --git a/depends/packages/capnp.mk b/depends/packages/capnp.mk
index 47df202771..6d792db711 100644
--- a/depends/packages/capnp.mk
+++ b/depends/packages/capnp.mk
@@ -4,18 +4,15 @@ $(package)_download_path=$(native_$(package)_download_path)
 $(package)_download_file=$(native_$(package)_download_file)
 $(package)_file_name=$(native_$(package)_file_name)
 $(package)_sha256_hash=$(native_$(package)_sha256_hash)
-$(package)_dependencies=native_$(package)
 
 define $(package)_set_vars :=
-$(package)_config_opts := --with-external-capnp
-$(package)_config_opts += --without-openssl
-$(package)_config_opts += CAPNP="$$(native_capnp_prefixbin)/capnp"
-$(package)_config_opts += CAPNP_CXX="$$(native_capnp_prefixbin)/capnp-c++"
-$(package)_config_opts_android := --disable-shared
+  $(package)_config_opts := -DBUILD_TESTING=OFF
+  $(package)_config_opts += -DWITH_OPENSSL=OFF
+  $(package)_config_opts += -DWITH_ZLIB=OFF
 endef
 
 define $(package)_config_cmds
-  $($(package)_autoconf)
+  $($(package)_cmake) .
 endef
 
 define $(package)_build_cmds
@@ -25,3 +22,7 @@ endef
 define $(package)_stage_cmds
   $(MAKE) DESTDIR=$($(package)_staging_dir) install
 endef
+
+define $(package)_postprocess_cmds
+  rm -rf lib/pkgconfig
+endef
diff --git a/depends/packages/native_capnp.mk b/depends/packages/native_capnp.mk
index ad87eed354..484e78d5d9 100644
--- a/depends/packages/native_capnp.mk
+++ b/depends/packages/native_capnp.mk
@@ -6,11 +6,13 @@ $(package)_file_name=capnproto-cxx-$($(package)_version).tar.gz
 $(package)_sha256_hash=0f7f4b8a76a2cdb284fddef20de8306450df6dd031a47a15ac95bc43c3358e09
 
 define $(package)_set_vars
-  $(package)_config_opts = --without-openssl
+  $(package)_config_opts := -DBUILD_TESTING=OFF
+  $(package)_config_opts += -DWITH_OPENSSL=OFF
+  $(package)_config_opts += -DWITH_ZLIB=OFF
 endef
 
 define $(package)_config_cmds
-  $($(package)_autoconf)
+  $($(package)_cmake) .
 endef
 
 define $(package)_build_cmds
@@ -20,3 +22,7 @@ endef
 define $(package)_stage_cmds
   $(MAKE) DESTDIR=$($(package)_staging_dir) install
 endef
+
+define $(package)_postprocess_cmds
+  rm -rf lib/pkgconfig
+endef
diff --git a/depends/packages/native_libmultiprocess.mk b/depends/packages/native_libmultiprocess.mk
index ea08eefea6..2e30be434c 100644
--- a/depends/packages/native_libmultiprocess.mk
+++ b/depends/packages/native_libmultiprocess.mk
@@ -1,8 +1,8 @@
 package=native_libmultiprocess
-$(package)_version=8b8a4766ce0a1892b9e8a5eb73dc39821005e520
+$(package)_version=6aca5f389bacf2942394b8738bbe15d6c9edfb9b
 $(package)_download_path=https://github.com/chaincodelabs/libmultiprocess/archive
 $(package)_file_name=$($(package)_version).tar.gz
-$(package)_sha256_hash=475c0dc2357a2ff30e9a164e4c16dc8a6597a57c9193d646fa9cbf0a55c45d78
+$(package)_sha256_hash=2efeed53542bc1d8af3291f2b6f0e5d430d86a5e04e415ce33c136f2c226a51d
 $(package)_dependencies=native_capnp
 
 define $(package)_config_cmds
diff --git a/src/qt/bitcoin.cpp b/src/qt/bitcoin.cpp
index 52bd0767b3..af50ae0129 100644
--- a/src/qt/bitcoin.cpp
+++ b/src/qt/bitcoin.cpp
@@ -58,7 +58,7 @@
 #include <QTimer>
 #include <QTranslator>
 
-#if defined(QT_STATICPLUGIN)
+#if defined(QT_STATIC)
 #include <QtPlugin>
 #if defined(QT_QPA_PLATFORM_XCB)
 Q_IMPORT_PLUGIN(QXcbIntegrationPlugin);
diff --git a/src/qt/guiutil.cpp b/src/qt/guiutil.cpp
index 649b009f25..cc261965b8 100644
--- a/src/qt/guiutil.cpp
+++ b/src/qt/guiutil.cpp
@@ -1862,12 +1862,8 @@ void LogQtInfo()
 #else
     const std::string qt_link{"dynamic"};
 #endif
-#ifdef QT_STATICPLUGIN
-    const std::string plugin_link{"static"};
-#else
-    const std::string plugin_link{"dynamic"};
-#endif
-    LogPrintf("Qt %s (%s), plugin=%s (%s)\n", qVersion(), qt_link, QGuiApplication::platformName().toStdString(), plugin_link);
+    // TODO replace instances of LogPrintf with LogInfo once 28318 is merged
+    LogPrintf("Qt %s (%s), plugin=%s\n", qVersion(), qt_link, QGuiApplication::platformName().toStdString());
     const auto static_plugins = QPluginLoader::staticPlugins();
     if (static_plugins.empty()) {
         LogPrintf("No static plugins.\n");
diff --git a/src/qt/test/test_main.cpp b/src/qt/test/test_main.cpp
index 34ea983441..4bf49ba8a0 100644
--- a/src/qt/test/test_main.cpp
+++ b/src/qt/test/test_main.cpp
@@ -25,7 +25,7 @@
 #include <QTest>
 #include <functional>
 
-#if defined(QT_STATICPLUGIN)
+#if defined(QT_STATIC)
 #include <QtPlugin>
 #if defined(QT_QPA_PLATFORM_MINIMAL)
 Q_IMPORT_PLUGIN(QMinimalIntegrationPlugin);
diff --git a/src/randomenv.cpp b/src/randomenv.cpp
index 05aa0c2d2c..ddb8983c6c 100644
--- a/src/randomenv.cpp
+++ b/src/randomenv.cpp
@@ -57,8 +57,10 @@
 #include <sys/auxv.h>
 #endif
 
+#ifndef _MSC_VER
 //! Necessary on some platforms
-extern char** environ;
+extern char** environ; // NOLINT(readability-redundant-declaration): Necessary on some platforms
+#endif
 
 namespace {