diff --git a/ci/test/00_setup_env_mac.sh b/ci/test/00_setup_env_mac.sh
index 01988889a9..fbbb6d8814 100755
--- a/ci/test/00_setup_env_mac.sh
+++ b/ci/test/00_setup_env_mac.sh
@@ -8,7 +8,7 @@ export LC_ALL=C.UTF-8
 
 export CONTAINER_NAME=ci_macos_cross
 export HOST=x86_64-apple-darwin
-export PACKAGES="cmake libz-dev libtinfo5 python3-setuptools xorriso"
+export PACKAGES="cmake libz-dev python3-setuptools xorriso"
 export XCODE_VERSION=12.2
 export XCODE_BUILD_ID=12B45b
 export RUN_UNIT_TESTS=false
diff --git a/contrib/guix/manifest.scm b/contrib/guix/manifest.scm
index bc9d6c9afa..51bfad9527 100644
--- a/contrib/guix/manifest.scm
+++ b/contrib/guix/manifest.scm
@@ -609,7 +609,7 @@ inspecting signatures in Mach-O binaries.")
            (list ;; Native GCC 11 toolchain
                  gcc-toolchain-11
                  binutils
-                 clang-toolchain-11
+                 clang-toolchain-15
                  python-signapple
                  xorriso))
           (else '())))))
diff --git a/depends/README.md b/depends/README.md
index 3717ee3d8c..1d18b1f780 100644
--- a/depends/README.md
+++ b/depends/README.md
@@ -47,7 +47,7 @@ The paths are automatically configured and no other options are needed unless ta
 
 #### For macOS cross compilation
 
-    sudo apt-get install curl bsdmainutils cmake libz-dev python3-setuptools libtinfo5 xorriso
+    sudo apt-get install curl bsdmainutils cmake libz-dev python3-setuptools xorriso
 
 Note: You must obtain the macOS SDK before proceeding with a cross-compile.
 Under the depends directory, create a subdirectory named `SDKs`.
diff --git a/depends/packages/native_clang.mk b/depends/packages/native_clang.mk
index 109796c0e6..661b9c2c1c 100644
--- a/depends/packages/native_clang.mk
+++ b/depends/packages/native_clang.mk
@@ -1,12 +1,12 @@
 package=native_clang
-$(package)_version=11.1.0
+$(package)_version=15.0.6
 $(package)_download_path=https://github.com/llvm/llvm-project/releases/download/llvmorg-$($(package)_version)
 ifneq (,$(findstring aarch64,$(BUILD)))
 $(package)_file_name=clang+llvm-$($(package)_version)-aarch64-linux-gnu.tar.xz
-$(package)_sha256_hash=18df38247af3fba0e0e2991fb00d7e3cf3560b4d3509233a14af699ef0039e1c
+$(package)_sha256_hash=8ca4d68cf103da8331ca3f35fe23d940c1b78fb7f0d4763c1c059e352f5d1bec
 else
-$(package)_file_name=clang+llvm-$($(package)_version)-x86_64-linux-gnu-ubuntu-16.04.tar.xz
-$(package)_sha256_hash=c691a558967fb7709fb81e0ed80d1f775f4502810236aa968b4406526b43bee1
+$(package)_file_name=clang+llvm-$($(package)_version)-x86_64-linux-gnu-ubuntu-18.04.tar.xz
+$(package)_sha256_hash=38bc7f5563642e73e69ac5626724e206d6d539fbef653541b34cae0ba9c3f036
 endif
 
 define $(package)_stage_cmds